Manufacturing

APOTEX PHARMACHEM INC. BRANTFORD, ONTARIO

Since its inception Apotex Pharmachem has continued to expand and refine its manufacturing capabilities to meet customer needs. State-of-the-art kilo-lab, pilot plant, and manufacturing facilities allow Apotex Pharmachem to simultaneously manufacture up to ten different active pharmaceutical ingredients at its Brantford, Ontario facility. This facility has been designed to ensure maximum flexibility and to carry out a wide variety of chemistries in a safe and environmentally sound manner while maintaining GMP compliance.

Apotex Pharmachem's 50,000 ft² Brantford production facility currently consists of eleven manufacturing work centres that have a reactor capacity range from 50 L to 5000 L, a process development kilo-lab, and preparative HPLC capability.

Innovation is central in our approach to Apotex Pharmachem's production; we are adept at devising technological solutions to satisfy unique and challenging customer requirements.

Plant Capabilities

  • Standard Operating Temperature Range: - 15 °C to 140 °C
  • High pressure/high vacuum operating ranges
  • Low & High Temperatures Capability from: - 80 °C to 200 °C
  • Specialized facilities and systems for HIGH Potency Active Pharmaceutical Ingredients (HPAPIs)
  • Solvent recovery and recycling

Apotex Pharmachem's Brantford finished product processing areas are built to class 100,000 clean room specifications. The Apotex Pharmachem manufacturing facilities utilize five different product drying technologies: vacuum tray, agitated vacuum pan, vacuum rotary double cone, fluid bed and spray. Multiple milling and micronization technologies are also present to achieve customer’s particle size requirements.